Map2k5 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comMap2k5 Polyclonal Antibody for Rat(Rattus norvegicus)

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Map2k5 (Gene name),

Dual specificity mitogen-activated protein kinase kinase 5 (Protein name ), MP2K5_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Map2k5(Mek5;Mkk5;Prkmk5);

Protein name:

Dual specificity mitogen-activated protein kinase kinase 5(MAP kinase kinase 5;MAPKK 5);

Alternative:

MAPK/ERK kinase 5(MEK 5);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with PARD6A, MAP3K3 and MAPK7. Forms a complex with SQSTM1 and PRKCZ or PRKCI.

Function:

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

Subcellular Location:

Isoform Alpha-2 Membrane The alternatively spliced exon in alpha isoform resemble conserved sequences that mediate interactions with the cytoskeleton, thereby explaining the differential localization.

Protein Attributes:

Sequence length:

448

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

448:

RKQPKERPAP | EELMGHPFIV | QFNDGNATVV | SMWVCRALEE | RRSQQGPP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q62862

UniGene:

Rn.11054

Pfam:

PF00564

String:

Q62862

KEGG:

rno:29568

Uniprot:

Q62862

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ELISA Kit for Rat MAP kinase kinase 5

Cat.:

E10343h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat MAP kinase kinase 5

Cat.:

E10343m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat MAP kinase kinase 5

Cat.:

E10343r

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MSDS:

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Packing:

96T

CLIA Kit for Rat MAP kinase kinase 5

Cat.:

U10343h

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Rat MAP kinase kinase 5

Cat.:

U10343r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MAP kinase kinase 5

Cat.:

U10343m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat MAP kinase kinase 5

Cat.:

P10343Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MAP kinase kinase 5

Protein for Rat MAP kinase kinase 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Isolation of MEK5 and differential expression of alternatively spliced forms."
English J.M. , Vanderbilt C.A. , Xu S. , Marcus S. , Cobb M.H.
J. Biol. Chem.270:28897-28902(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA-1; ALPHA-2 AND BETA);FUNCTION;MUTAGENESIS
strain: Sprague-Dawley.
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA-1)
tissue: Lung.

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